Oguro Hiroaki, Ward Robert, Bracewel Martyn, Hindle John, Rafal Robert
Department of Neurology, Shimane University, Faculty of Medicine, Japan.
Neurosci Lett. 2009 Sep 29;463(1):35-6. doi: 10.1016/j.neulet.2009.07.033. Epub 2009 Jul 16.
Clinical observations of kinesia paradoxica and freezing in patients with Parkinson's disease suggest that the automatic activation of motor programmes by visual stimuli may not require intact basal ganglia function, and that an increased sensitivity to such object affordances may contribute to some symptoms of the disease. Employing a paradigm that measures the degree of interference from object affordances on voluntary actions, we confirm that activation of object affordances are preserved in Parkinson's disease, but find no evidence that there is an increased sensitivity to the effects of object affordances on voluntary action.
帕金森病患者运动不能性异动症和冻结现象的临床观察表明,视觉刺激对运动程序的自动激活可能不需要完整的基底神经节功能,并且对这种物体可供性的敏感性增加可能导致该疾病的一些症状。采用一种测量物体可供性对自主行动干扰程度的范式,我们证实帕金森病患者中物体可供性的激活是存在的,但没有证据表明对物体可供性对自主行动影响的敏感性增加。