Javitt J C, Aiello L P, Bassi L J, Chiang Y P, Canner J K
Worthen Center for Eye Care Research, Center for Sight, Georgetown University Medical Center, Washington 20007.
Ophthalmology. 1991 Oct;98(10):1565-73; discussion 1574.
Diabetic retinopathy is the leading cause of acquired blindness among Americans of working age. The resulting economic and societal burdens are of profound magnitude. Epidemiologic and clinical trials data were used to analyze the impact of improved recruitment of patients with Type I diabetes mellitus into screening and treatment programs. The analysis predicted annual savings of $101.0 million and 47,374 person-years-sight at the currently estimated 60% screening and treatment implementation level. If all patients received appropriate eye care, the predicted savings exceed 167.0 million and 79,236 person-years-sight. Approximately two thirds of all savings result from treatment of proliferative diabetic retinopathy, while nearly one third arises from treatment of clinically significant macular edema. Additional savings of $9571 are realized with each recruitment of a newly diagnosed patient with diabetes. Initiating screening immediately upon diagnosis of diabetes, rather than the currently recommended 5-year deferral, would be cost effective if 1 additional individual in 56 were recruited. This model suggests that improved delivery of ophthalmic care to patients with diabetes would yield substantial financial and visual savings, thus making major recruitment programs such as the National Eye Institute's National Eye Health Education Program and the American Academy of Ophthalmology's Diabetes 2000, both economically and clinically effective.
糖尿病性视网膜病变是美国工作年龄段人群后天失明的主要原因。由此产生的经济和社会负担极为巨大。利用流行病学和临床试验数据来分析改善1型糖尿病患者参与筛查和治疗项目招募工作的影响。该分析预测,在目前估计60%的筛查和治疗实施水平下,每年可节省1.01亿美元,并挽救47374人年的视力。如果所有患者都能得到适当的眼部护理,预计节省将超过1.67亿美元,挽救79236人年的视力。所有节省中约三分之二来自增殖性糖尿病性视网膜病变的治疗,近三分之一来自临床显著性黄斑水肿的治疗。每招募一名新诊断的糖尿病患者还可额外节省9571美元。如果每56名患者中有1名额外患者被招募,在糖尿病诊断后立即开始筛查,而不是目前建议的推迟5年,将具有成本效益。该模型表明,改善糖尿病患者的眼科护理服务将带来可观的经济和视力方面的节省,从而使诸如国立眼科研究所的国家眼健康教育项目和美国眼科学会的糖尿病2000等大型招募项目在经济和临床方面都具有成效。