Mraz Krista D, Dixon James, Dumont-Mathieu Thyde, Fein Deborah
Department of Psychology, University of Connecticut, Connecticut, USA.
J Child Neurol. 2009 Jul;24(7):833-45. doi: 10.1177/0883073808331345.
Previous research has demonstrated accelerated head and body growth during infancy in children with autism spectrum disorders. No study has yet examined head growth in children who lose their autism spectrum disorder diagnoses. Head circumference, length, and weight growth during infancy for 24 children who maintained their diagnoses were compared with 15 children who lost their diagnoses, and to 37 typically developing controls. Results showed that head circumference and weight growth were significantly greater in both autism spectrum disorder groups compared with controls, with no significant differences between autism spectrum disorder groups. However, when length and weight were controlled for, accelerated head growth remained significant in the children who lost their diagnoses. Findings suggest that children who lose their autism spectrum disorder diagnoses and children who maintain their diagnoses show similar head circumference, length, and weight growth trajectories during infancy, although subtle differences in body growth between groups may exist.
先前的研究表明，患有自闭症谱系障碍的儿童在婴儿期头部和身体生长加速。尚未有研究考察过那些不再被诊断为自闭症谱系障碍的儿童的头部生长情况。将24名维持自闭症谱系障碍诊断的儿童在婴儿期的头围、身长和体重增长情况与15名不再被诊断为自闭症谱系障碍的儿童以及37名发育正常的对照组儿童进行了比较。结果显示，与对照组相比，两个自闭症谱系障碍组的头围和体重增长显著更大，而自闭症谱系障碍组之间无显著差异。然而，在对身长和体重进行控制后，不再被诊断为自闭症谱系障碍的儿童的头部加速生长仍然显著。研究结果表明，那些不再被诊断为自闭症谱系障碍的儿童和维持诊断的儿童在婴儿期头围、身长和体重的生长轨迹相似，尽管两组之间在身体生长方面可能存在细微差异。
