Department of Psychology, University of Connecticut, Storrs, Connecticut, USA.
Autism Res. 2013 Dec;6(6):605-13. doi: 10.1002/aur.1324. Epub 2013 Aug 8.
The autism spectrum disorders (ASD) are neurodevelopmental disorders diagnosed behaviorally but associated with differences in brain development. Individuals with ASD exhibit superior auditory perceptual skills, which may correlate with ASD symptomatology, particularly language skills. We describe findings from individuals diagnosed with ASD before age five, who now have no symptoms (e.g., having optimal outcomes). Unlike an ASD group, which shows heightened pitch discrimination, the Optimal Outcome group's abilities do not differ from those of typically developing controls. Furthermore, pitch discrimination is associated with both current autism symptomatology and early-language milestones. Findings illuminate processes associated with resolution of autism. We also discuss a specific mechanism by which heightened auditory discrimination leads to language delays in ASD.
自闭症谱系障碍（ASD）是一种行为诊断的神经发育障碍，但与大脑发育的差异有关。自闭症患者表现出卓越的听觉感知能力，这可能与自闭症的症状相关，特别是语言技能。我们描述了在五岁之前被诊断为自闭症的个体的发现，他们现在没有症状（例如，有最佳的结果）。与表现出更高音调辨别力的 ASD 组不同，最佳结果组的能力与正常发育对照组没有差异。此外，音调辨别力与当前的自闭症症状和早期语言里程碑都有关。这些发现阐明了与自闭症缓解相关的过程。我们还讨论了一种特定的机制，即增强的听觉辨别力如何导致 ASD 中的语言延迟。
