Nakata Hiroki, Sakamoto Kiwako, Inui Koji, Hoshiyama Minoru, Kakigi Ryusuke
Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan.
Neuroreport. 2009 Aug 26;20(13):1149-54. doi: 10.1097/WNR.0b013e32832f81d6.
The objective of this study was to investigate whether no-go potentials during go/no-go tasks were observed after painful stimulation using intraepidermal electrical stimulation. Event-related potentials were recorded by stimulating the medial or lateral side of the left-hand dorsum. Peak amplitudes of N2 and P3 were significantly larger in no-go trials than in go trials at frontocentral electrodes during go/no-go task, but the differences were not found during rest control and choice reaction time tasks. These characteristics of no-go-related potentials were very similar to event-related potential waveforms during visual, auditory, and somatosensory go/no-go tasks. We suggest that cortical activities relating to response inhibitory processing are not dependent on the sensory modality used.
本研究的目的是调查使用表皮内电刺激进行疼痛刺激后,在“是/否”任务中是否观察到“否”反应电位。通过刺激左手背的内侧或外侧来记录事件相关电位。在“是/否”任务期间,额中央电极处,“否”试验中N2和P3的峰值幅度显著大于“是”试验,但在静息对照和选择反应时任务中未发现差异。这些与“否”相关电位的特征与视觉、听觉和体感“是/否”任务期间的事件相关电位波形非常相似。我们认为,与反应抑制处理相关的皮层活动不依赖于所使用的感觉模态。