Mahmood Amal, Idrees Romana, Vohra Lubna Mushtaque
Medical Student, Bachelor of Medicine and Bachelor of Surgery (MBBS), Aga Khan University, Karachi, Pakistan.
Associate Professor, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Int J Surg Case Rep. 2025 Jan;126:110702. doi: 10.1016/j.ijscr.2024.110702. Epub 2024 Nov 29.
Idiopathic Granulomatous Mastitis is a rare benign inflammatory disease of the breast.
We present a case of 45-year-old woman who was diagnosed with stage II invasive ductal carcinoma in the left breast. While receiving neoadjuvant chemotherapy, she developed idiopathic granulomatous mastitis (IGM) in the left breast after the second cycle. She underwent modified radical mastectomy and has been managed with steroids for IGM on the contralateral side, which developed later in the course of the disease. This is a unique finding with limited literature available on similar cases, to the best of our knowledge.
IGM poses a diagnostic challenge requiring histopathology for definitive diagnosis.
Treatment guidelines of IGM are not established making it difficult to manage.
特发性肉芽肿性乳腺炎是一种罕见的乳腺良性炎症性疾病。
我们报告一例45岁女性，其被诊断为左乳II期浸润性导管癌。在接受新辅助化疗时，她在第二个周期后左乳发生了特发性肉芽肿性乳腺炎（IGM）。她接受了改良根治性乳房切除术，并对疾病后期在对侧发生的IGM使用类固醇进行治疗。据我们所知，这是一个独特的发现，关于类似病例的文献有限。
IGM带来了诊断挑战，需要组织病理学进行明确诊断。
IGM的治疗指南尚未确立，这使得管理变得困难。
