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Systematizing serendipity for cardiovascular drug discovery.

作者信息

Schlueter Peter J, Peterson Randall T

机构信息

Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

出版信息

Circulation. 2009 Jul 21;120(3):255-63. doi: 10.1161/CIRCULATIONAHA.108.824177.

Abstract
摘要

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本文引用的文献

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Identifying the proteins to which small-molecule probes and drugs bind in cells.确定小分子探针和药物在细胞中所结合的蛋白质。
Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4617-22. doi: 10.1073/pnas.0900191106. Epub 2009 Mar 2.
3
Chemical biology and the limits of reductionism.化学生物学与还原论的局限
Nat Chem Biol. 2008 Nov;4(11):635-8. doi: 10.1038/nchembio1108-635.
9
Targeted gene expression by the Gal4-UAS system in zebrafish.Gal4-UAS系统在斑马鱼中的靶向基因表达。
Dev Growth Differ. 2008 Aug;50(6):391-9. doi: 10.1111/j.1440-169X.2008.01044.x. Epub 2008 May 14.
10
Cardiogenic small molecules that enhance myocardial repair by stem cells.通过干细胞增强心肌修复的心脏源性小分子。
Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6063-8. doi: 10.1073/pnas.0711507105. Epub 2008 Apr 17.

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