Arriagada S Daniela, Wilhelm B Jan, Donoso F Alejandro
Departamento de Pediatría, Facultad de Medicina, Clínica Alemana - Universidad del Desarrollo, Santiago, Chile.
Rev Chilena Infectol. 2009 Apr;26(2):162-7. Epub 2009 Jun 16.
Botulism is a rare disease in Chile and of the known clinical presentation, infant botulism is the most common. We report the case of a previously healthy seven month old male infant with a two weeks history of rinorrea, cough, fatigue, constipation and progressive weakness after the consumption of honey. Stool cultures were positive for Clostridium botulinum group 1 type A and electromyography was compatible with the diagnosis. The patient evolved with arterial hypertension, interpreted as secondary to autonomic dysfunction, which responded to calcium channel blockers. Muscle tone improved progressively during the following four weeks. Infant botulism is a potentially fatal disease; diagnosis can be difficult given the broad clinical manifestations. Prevention should focus on education of parents of infants as well as medical personnel.
肉毒中毒在智利是一种罕见疾病,在已知的临床表现中,婴儿肉毒中毒最为常见。我们报告一例病例,一名此前健康的7个月大男婴,在食用蜂蜜后出现两周的流涕、咳嗽、乏力、便秘及进行性肌无力病史。粪便培养显示A型1群肉毒杆菌阳性,肌电图检查结果符合诊断。患者出现动脉高血压,被解释为继发于自主神经功能障碍,对钙通道阻滞剂有反应。在接下来的四周内肌张力逐渐改善。婴儿肉毒中毒是一种潜在致命性疾病;鉴于临床表现广泛,诊断可能困难。预防应侧重于对婴儿家长及医务人员进行教育。