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在一个包含529,688例低风险计划在家分娩和医院分娩的全国性队列中的围产期死亡率和发病率。

Perinatal mortality and morbidity in a nationwide cohort of 529,688 low-risk planned home and hospital births.

作者信息

de Jonge A, van der Goes B Y, Ravelli A C J, Amelink-Verburg M P, Mol B W, Nijhuis J G, Bennebroek Gravenhorst J, Buitendijk S E

机构信息

TNO Quality of Life, Leiden, The Netherlands.

出版信息

BJOG. 2009 Aug;116(9):1177-84. doi: 10.1111/j.1471-0528.2009.02175.x.

Abstract

OBJECTIVE

To compare perinatal mortality and severe perinatal morbidity between planned home and planned hospital births, among low-risk women who started their labour in primary care.

DESIGN

A nationwide cohort study.

SETTING

The entire Netherlands.

POPULATION

A total of 529,688 low-risk women who were in primary midwife-led care at the onset of labour. Of these, 321,307 (60.7%) intended to give birth at home, 163,261 (30.8%) planned to give birth in hospital and for 45,120 (8.5%), the intended place of birth was unknown.

METHODS

Analysis of national perinatal and neonatal registration data, over a period of 7 years. Logistic regression analysis was used to control for differences in baseline characteristics.

MAIN OUTCOME MEASURES

Intrapartum death, intrapartum and neonatal death within 24 hours after birth, intrapartum and neonatal death within 7 days and neonatal admission to an intensive care unit.

RESULTS

No significant differences were found between planned home and planned hospital birth (adjusted relative risks and 95% confidence intervals: intrapartum death 0.97 (0.69 to 1.37), intrapartum death and neonatal death during the first 24 hours 1.02 (0.77 to 1.36), intrapartum death and neonatal death up to 7 days 1.00 (0.78 to 1.27), admission to neonatal intensive care unit 1.00 (0.86 to 1.16).

CONCLUSIONS

This study shows that planning a home birth does not increase the risks of perinatal mortality and severe perinatal morbidity among low-risk women, provided the maternity care system facilitates this choice through the availability of well-trained midwives and through a good transportation and referral system.

摘要

目的

比较在初级保健机构开始分娩的低风险女性中,计划在家分娩和计划在医院分娩的围产期死亡率及严重围产期发病率。

设计

一项全国性队列研究。

地点

荷兰全境。

研究对象

共有529,688名在分娩开始时接受初级助产士护理的低风险女性。其中,321,307名(60.7%)打算在家分娩,163,261名(30.8%)计划在医院分娩,45,120名(8.5%)的预期分娩地点未知。

方法

对7年期间的全国围产期和新生儿登记数据进行分析。采用逻辑回归分析来控制基线特征的差异。

主要观察指标

产时死亡、出生后24小时内的产时和新生儿死亡、7天内的产时和新生儿死亡以及新生儿入住重症监护病房情况。

结果

计划在家分娩和计划在医院分娩之间未发现显著差异(调整后的相对风险及95%置信区间:产时死亡0.97(0.69至1.37),出生后最初24小时内的产时和新生儿死亡1.02(0.77至1.36),7天内的产时和新生儿死亡1.00(0.78至1.27),新生儿入住重症监护病房1.00(0.86至1.16)。

结论

本研究表明,对于低风险女性,若产科护理系统通过提供训练有素的助产士以及良好的交通和转诊系统来便利这种选择,那么计划在家分娩并不会增加围产期死亡率和严重围产期发病率的风险。

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