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非剥脱性二氧化碳激光换肤治疗酒渣鼻的疗效和安全性——一项回顾性队列研究及问卷调查研究

Efficacy and safety of non-fractional ablative carbon dioxide laser resurfacing for the treatment of rhinophyma - a retrospective cohort and questionnaires-based study.

作者信息

Noyman Yehonatan, Friedman Hadas Ofer, Lapidoth Moshe, Harris Rimon Gaia, Solomon-Cohen Efrat, Snast Igor, Rozenblat Mati, Mimouni Daniel, Levi Assi

机构信息

Laser Unit, Division of Dermatology, Rabin Medical Center, Petah Tikva, Israel.

Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Lasers Med Sci. 2025 Jun 9;40(1):261. doi: 10.1007/s10103-025-04442-7.

DOI:10.1007/s10103-025-04442-7
PMID:40484919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12146221/
Abstract

PURPOSE

Phymatous rosacea is a chronic and disfiguring subtype of rosacea, mainly affecting the nose and leading to the development of rhinophyma. This condition manifests with erythema, enlarged pores and increased sebum secretion, progressing to textural alterations and nasal hypertrophy. Ablative CO laser resurfacing has emerged as a preferred approach, offering hemostatic control and favorable cosmetic outcomes. This case series presents our treatment experience with a non-fractional ablative CO laser resurfacing under local anesthesia for severe rhinophyma patients.

METHODS

A Retrospective case series of patients with severe rhinophyma treated with an ablative CO laser between December 2010 and March 2020 in our laser unit. Post-procedure aesthetic outcome was assessed by the treating physician 3 months following treatment and patients were asked to complete a long-term follow-up questionnaire.

RESULTS

Sixteen patients (15 males) were included, of which 13 patients (81%) had completed the questionnaire on an average of 15 months following treatment (range 2-24 months). Patient satisfaction following treatment was high, with an average satisfaction score of 7.9 out of 10 (range 4-10). Post-procedure aesthetic outcome was rated as very good or excellent in 13 patients (81%, with 75% or greater improvement). Among the 13 patients who completed the questionnaire, 11 (85%) indicated that they would recommend this treatment to others with a similar condition.

CONCLUSION

Non-fractional, ablative CO laser resurfacing performed under local anesthesia, has proven to be a safe, effective and well-tolerated treatment for severe rhinophyma, yielding sustainable results and high satisfaction rate.

摘要

目的

结节性酒渣鼻是酒渣鼻的一种慢性毁容性亚型,主要累及鼻子并导致鼻赘形成。这种疾病表现为红斑、毛孔粗大和皮脂分泌增加,进而发展为质地改变和鼻肥大。剥脱性CO₂激光换肤已成为一种首选方法,可实现止血控制并带来良好的美容效果。本病例系列介绍了我们在局部麻醉下对重度鼻赘患者进行非分次剥脱性CO₂激光换肤的治疗经验。

方法

回顾性病例系列,纳入2010年12月至2020年3月在我们激光治疗单元接受剥脱性CO₂激光治疗的重度鼻赘患者。治疗后3个月,由治疗医生评估术后美学效果,并要求患者完成一份长期随访问卷。

结果

纳入16例患者(15例男性),其中13例患者(81%)在治疗后平均15个月(范围2 - 24个月)完成了问卷。治疗后患者满意度较高,平均满意度评分为7.9分(满分10分,范围4 - 10分)。13例患者(81%,改善率达75%或更高)的术后美学效果被评为非常好或优秀。在完成问卷的13例患者中,11例(85%)表示他们会向其他患有类似疾病的人推荐这种治疗方法。

结论

局部麻醉下进行的非分次剥脱性CO₂激光换肤已被证明是一种安全、有效且耐受性良好的重度鼻赘治疗方法,能产生可持续的效果并具有较高的满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2515/12146221/3e3b8a867e61/10103_2025_4442_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2515/12146221/f66fe74c62f3/10103_2025_4442_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2515/12146221/3e3b8a867e61/10103_2025_4442_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2515/12146221/f66fe74c62f3/10103_2025_4442_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2515/12146221/3e3b8a867e61/10103_2025_4442_Fig2_HTML.jpg

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本文引用的文献

1
Rhinophyma in women: a case series.女性酒渣鼻:病例系列。
Lasers Med Sci. 2021 Aug;36(6):1283-1287. doi: 10.1007/s10103-020-03183-z. Epub 2021 Jan 7.
2
Using Local Anesthesia for Inguinal Hernia Repair Reduces Complications in Older Patients.局部麻醉用于腹股沟疝修补术可减少老年患者的并发症。
J Surg Res. 2021 Feb;258:64-72. doi: 10.1016/j.jss.2020.08.054. Epub 2020 Sep 28.
3
Rhinophyma: Prevalence, Severity, Impact and Management.鼻赘:患病率、严重程度、影响及管理
Clin Cosmet Investig Dermatol. 2020 Aug 11;13:537-551. doi: 10.2147/CCID.S201290. eCollection 2020.
4
Severe rhinophyma: Tips and tricks in carbon dioxide laser decortication.重度鼻赘:二氧化碳激光去皮术的技巧与窍门
J Am Acad Dermatol. 2020 Feb;82(2):e49-e50. doi: 10.1016/j.jaad.2019.01.060. Epub 2019 Jan 31.
5
Rhinophyma is associated with alcohol intake.鼻赘与酒精摄入有关。
J Am Acad Dermatol. 2019 Jul;81(1):249-250. doi: 10.1016/j.jaad.2018.12.046. Epub 2019 Jan 8.
6
Procedural management of rhinophyma: A comprehensive review.酒渣鼻的手术治疗:综述
J Cosmet Dermatol. 2018 Dec;17(6):960-967. doi: 10.1111/jocd.12770. Epub 2018 Sep 17.
7
Rosacea and rhinophyma.酒渣鼻和鼻赘。
Clin Dermatol. 2014 Jan-Feb;32(1):35-46. doi: 10.1016/j.clindermatol.2013.05.024.
8
Anesthesia methods in laser resurfacing.激光换肤中的麻醉方法。
Semin Plast Surg. 2012 Aug;26(3):117-24. doi: 10.1055/s-0032-1329416.
9
Surgical correction of rhinophyma: comparison of two methods in a 15-year-long experience.外科矫正酒渣鼻:15 年长期经验中的两种方法比较。
J Craniomaxillofac Surg. 2013 Jul;41(5):429-36. doi: 10.1016/j.jcms.2012.11.009. Epub 2012 Dec 8.
10
Carbon dioxide laser treatment of rhinophyma: a review of 124 patients.二氧化碳激光治疗酒渣鼻:124 例患者回顾。
Br J Dermatol. 2009 Oct;161(4):814-8. doi: 10.1111/j.1365-2133.2009.09317.x. Epub 2009 Jul 14.