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二氧化碳激光治疗中重度酒渣鼻的长期满意度:一项单中心研究。

Long-term Satisfaction with CO2 Laser Treatment for Moderate to Major Rhinophyma: A Single-centre Study.

作者信息

Olafsdottir Berta, Jebril William, Curman Philip, Bachar-Wikström Etty, Wikström Jakob D

机构信息

Dermatology and Venereology Division, Department of Medicine (Solna), Karolinska Institutet, Stockholm, Sweden.

Dermatology and Venereology Division, Department of Medicine (Solna), Karolinska Institutet, Stockholm, Sweden; Dermato-Venereology Clinic, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Acta Derm Venereol. 2025 Jan 3;105:adv41335. doi: 10.2340/actadv.v105.41335.

DOI:10.2340/actadv.v105.41335
PMID:39749392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11697134/
Abstract

Rhinophyma, a severe manifestation of rosacea, predominantly affects Caucasian males aged 50-70 and is characterized by thickening and enlargement of the nasal skin. The condition can seriously both impact cosmetic appearance and obstruct nasal breathing. While its appearance is distinct, conditions such as basal cell carcinoma can mimic it, complicating diagnosis. Treatment options for rhinophyma range from medical therapies to surgical interventions, with CO2 laser resurfacing emerging as the gold standard due to its precision and minimal blood loss. This retrospective case series evaluates the long-term efficacy and patient satisfaction of CO2 laser treatment in 11 male patients treated between 2015 and 2023 at the Karolinska University Hospital. The results revealed sustained positive outcomes, with 92% of patients reporting high satisfaction and 55% experiencing improved nasal airflow post-procedure. Despite some instances of hypopigmentation and scarring, no major side effects were reported. The study supports CO2 laser treatment as a safe and effective option for moderate to major rhinophyma in Caucasian male patients with Fitzpatrick skin types I-III. The importance of considering skin type, where extra caution must be employed when treating skin types IV-VI, should be emphasized as the treatment.

摘要

酒渣鼻性痤疮是酒渣鼻的一种严重表现形式,主要影响年龄在50至70岁的白种男性,其特征为鼻皮肤增厚和肿大。这种病症会严重影响外观并阻碍鼻腔呼吸。虽然其外观独特,但诸如基底细胞癌等病症可能会与之相似,从而使诊断变得复杂。酒渣鼻性痤疮的治疗选择从药物治疗到手术干预不等,由于其精确性和最小出血量,二氧化碳激光表面重塑已成为金标准。本回顾性病例系列评估了2015年至2023年在卡罗林斯卡大学医院接受治疗的11名男性患者中二氧化碳激光治疗的长期疗效和患者满意度。结果显示出持续的积极效果,92%的患者报告高度满意,55%的患者在术后鼻腔气流得到改善。尽管有一些色素沉着不足和瘢痕形成的情况,但未报告重大副作用。该研究支持二氧化碳激光治疗作为 Fitzpatrick皮肤类型I - III的白种男性患者中重度至重度酒渣鼻性痤疮的一种安全有效的选择。应强调在治疗时考虑皮肤类型的重要性,在治疗IV - VI型皮肤时必须格外谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f531/11697134/004e9270526b/ActaDV-105-41335-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f531/11697134/005ea3dd3294/ActaDV-105-41335-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f531/11697134/004e9270526b/ActaDV-105-41335-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f531/11697134/005ea3dd3294/ActaDV-105-41335-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f531/11697134/004e9270526b/ActaDV-105-41335-g002.jpg

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本文引用的文献

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A Case of Complex Giant Rhinophyma Treated With Cosmetic Surgery.一例采用美容手术治疗的复杂巨大型酒渣鼻
Ann Plast Surg. 2024 Aug 1;93(2S Suppl 1):S27-S29. doi: 10.1097/SAP.0000000000004001. Epub 2024 Jun 17.
2
Rhinophyma in women: a case series.女性酒渣鼻:病例系列。
Lasers Med Sci. 2021 Aug;36(6):1283-1287. doi: 10.1007/s10103-020-03183-z. Epub 2021 Jan 7.
3
Fractionated Carbon Dioxide Laser Resurfacing as an Ideal Treatment Option for Severe Rhinophyma: A Case Report and Discussion.分次二氧化碳激光换肤术作为重度酒渣鼻的理想治疗选择:病例报告与讨论
J Clin Aesthet Dermatol. 2019 Jan;12(1):24-27. Epub 2019 Jan 1.
4
Procedural management of rhinophyma: A comprehensive review.酒渣鼻的手术治疗:综述
J Cosmet Dermatol. 2018 Dec;17(6):960-967. doi: 10.1111/jocd.12770. Epub 2018 Sep 17.
5
Incidence and prevalence of rosacea: a systematic review and meta-analysis.酒渣鼻的发病率和患病率:系统评价和荟萃分析。
Br J Dermatol. 2018 Aug;179(2):282-289. doi: 10.1111/bjd.16481. Epub 2018 May 31.
6
Rosacea.酒渣鼻
Aust Fam Physician. 2017;46(5):277-281.
7
Fractionated ablative carbon dioxide laser for the treatment of rhinophyma.分次消融二氧化碳激光治疗酒渣鼻。
Lasers Surg Med. 2014 Jan;46(1):8-12. doi: 10.1002/lsm.22184. Epub 2013 Oct 5.
8
Carbon dioxide laser treatment of rhinophyma: a review of 124 patients.二氧化碳激光治疗酒渣鼻:124 例患者回顾。
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