Tang Thomas, Balen Adam H
Department of Obstetrics and Gynaecology, St James's University Hospital, University of Leeds, Leeds, UK.
Nat Rev Endocrinol. 2009 Aug;5(8):462-5. doi: 10.1038/nrendo.2009.125.
A 25-year-old South Asian woman presented at an infertility unit with a 2-year history of anovulatory infertility. She had experienced irregular and infrequent periods for over a decade.
Endocrine profile (follicle-stimulating hormone, luteinizing hormone, thyroid-function test, prolactin, testosterone), oral glucose tolerance test and pelvic ultrasonography were performed.
Polycystic ovary syndrome, in accordance with the recent Rotterdam consensus (2004) criteria.
The patient failed to conceive by conventional ovulation-induction therapies with clomifene and gonadotropins. She subsequently underwent an in vitro fertilization cycle, to which she over-responded and developed a severe form of ovarian hyperstimulation syndrome. The diagnosis of ovarian hyperstimulation syndrome was based on clinical and ultrasonographic features. She was hospitalized and needed extensive supportive care, including insertion of chest and abdominal drains.
一名25岁的南亚女性因无排卵性不孕2年就诊于一家不孕不育科。她经历月经不规律且稀少已超过十年。
进行了内分泌检查（促卵泡生成素、促黄体生成素、甲状腺功能检查、催乳素、睾酮）、口服葡萄糖耐量试验及盆腔超声检查。
根据最新的鹿特丹共识（2004年）标准，诊断为多囊卵巢综合征。
该患者采用克罗米芬和促性腺激素进行传统的促排卵治疗未能受孕。随后她接受了体外受精周期治疗，但出现过度反应并发展为严重形式的卵巢过度刺激综合征。卵巢过度刺激综合征的诊断基于临床和超声特征。她住院并需要广泛的支持治疗，包括插入胸腔和腹腔引流管。
