Programme National de Lutte contre la Bilharziose et les Géohelminthes, Ministère de la Santé Publique, 2648 Bd du Zarmaganda, B.P. 13724, Niamey, Niger.
Parasitology. 2009 Nov;136(13):1731-7. doi: 10.1017/S0031182009990369. Epub 2009 Jul 27.
Since 2004 the West African countries of Burkina Faso, Mali and Niger have implemented national schistosomiasis and soil-transmitted helminthiasis control programmes with financial and technical support from the Schistosomiasis Control Initiative (SCI). In the first three years of the control programmes, nearly 13.5 million doses of praziquantel and albendazole have been administered against schistosomiasis and soil-transmitted helminthiasis with coverage rates varying between 67.0% and 93.9%. These treatments have resulted in a reduction of the prevalence and intensity of Schistosoma infection in the sentinel cohorts that were set up to monitor and evaluate the national control programmes. The challenges currently faced by these national control programmes are the ability to maintain the reduction in morbidity achieved thus far due to the mass treatment campaigns and ensuring sustainability. For reinforcement of surveillance, the establishment of a geographical information system is suggested in order to contribute towards enhanced sustainability of these programmes. Our new working hypothesis is that targeted control accompanied by periodic mass treatment campaigns (every two to three years) can contribute to maintaining the low levels of morbidity achieved thus far. The implementation of integrated neglected tropical disease control programmes in these countries will provide means to ensure the financial sustainability of control activities for the years to come.
自 2004 年以来,布基纳法索、马里和尼日尔等西非国家在血吸虫病控制倡议(SCI)的财政和技术支持下,实施了国家血吸虫病和土壤传播性蠕虫病控制规划。在控制规划的头三年中,针对血吸虫病和土壤传播性蠕虫病共使用了近 1350 万剂吡喹酮和阿苯达唑,覆盖率在 67.0%至 93.9%之间。这些治疗措施导致在设立以监测和评估国家控制规划的哨点队列中,血吸虫感染的流行率和强度有所降低。这些国家控制规划目前面临的挑战是,能否保持迄今为止通过大规模治疗运动取得的发病率降低,并确保可持续性。为了加强监测,建议建立地理信息系统,以促进这些规划的可持续性增强。我们的新工作假设是,有针对性的控制加上定期的大规模治疗运动(每两到三年一次)可以有助于维持迄今为止实现的低发病率水平。在这些国家实施综合被忽视的热带病控制规划将为未来几年的控制活动提供资金可持续性的保障。