Hellio Le Graverand Marie-Pierre, Mazzuca Steve, Duryea Jeff, Brett Alan
Clinical Development and Medical Affairs, Inflammation, Specialty Care Business Unit, Pfizer Inc., 50 Pequot Avenue, New London, CT 06320, USA.
Radiol Clin North Am. 2009 Jul;47(4):567-79. doi: 10.1016/j.rcl.2009.04.004.
Accurate and highly reproducible measurements of the rate of progression of osteoarthritis is crucial to assessing structural change, and requires adherence to exacting standards of positioning, which include specifications for flexion and rotation of the joint, and angulation of the x-ray beam. The progression of osteoarthritis traditionally has been measured using radiographic joint space width (JSW). Over the past two decades, numerous knee radiographic protocols have been developed with various levels of complexity and performance as they relate to detecting JSW loss (ie, joint space narrowing). Semiautomated software has been developed to improve the accuracy of JSW measurement over manual methods. JSW measurements include minimum JSW, mean JSW or joint space area and JSW at fixed locations.
准确且高度可重复地测量骨关节炎的进展速率对于评估结构变化至关重要，并且需要严格遵守定位标准，其中包括关节屈伸和旋转的规范以及X射线束的角度。传统上，骨关节炎的进展是通过放射学关节间隙宽度（JSW）来测量的。在过去二十年中，已经开发了许多膝关节放射学检查方案，其复杂性和性能各不相同，与检测JSW损失（即关节间隙变窄）有关。已经开发了半自动软件以提高JSW测量相对于手动方法的准确性。JSW测量包括最小JSW、平均JSW或关节间隙面积以及固定位置处的JSW。
