Centro de Investigacións Mariñas (Xunta de Galicia), Apto. 13, 36620 Vilanova de Arousa, Pontevedra, Spain.
Toxicon. 2010 Feb-Mar;55(2-3):638-41. doi: 10.1016/j.toxicon.2009.07.014. Epub 2009 Jul 23.
In an attempt to evaluate the risk for human consumption associated to the accumulation of lipophilic toxins by two commercially important bivalves: macha (Mesodesma donacium) and clam (Mulinia edulis) in Coquimbo Bay (Chile), monitoring of these species was carried out from March to September 2008. The samples were analyzed by liquid chromatography-mass spectrometry (LC-MS) to detect okadaic acid, dinophysistoxins, pectenotoxins, azaspiracids, yessotoxins and spirolides. Low levels of Azaspiracid-1 and 13-desmethyl C spirolide were found in both species. The toxins were detected at different dates throughout the monitoring period and in some cases both toxins were detected in the same sample. In all cases, the concentration of the toxins was below the limit of quantification of the technique used and therefore these detections are only indicative of a potential risk. This is the first report of the occurrence of these groups of toxins in Chile and suggests that it is necessary to monitor routinely these substances to warrant public health and shellfish exportations.
为了评估智利科金博湾（Coquimbo Bay）两种商业上重要的双壳贝类——贻贝（Mesodesma donacium）和蚬（Mulinia edulis）体内脂溶性毒素积累对人类食用的风险，于 2008 年 3 月至 9 月对这两种贝类进行了监测。采用液相色谱-质谱（LC-MS）法对这些样本进行分析，以检测 okadaic 酸、麻痹性贝类毒素、膝沟藻毒素、扇贝毒素、短裸甲藻毒素和石房蛤毒素。在这两种贝类中均检测到低浓度的 Azaspiracid-1 和 13-去甲基 C 石房蛤毒素。在整个监测期间的不同日期都检测到了这些毒素，在某些情况下，同一批样本中同时检测到了这两种毒素。在所有情况下，毒素的浓度都低于所用技术的定量限，因此这些检测结果仅表明存在潜在风险。这是智利首次报告这些毒素组的存在，表明有必要定期监测这些物质，以保障公众健康和贝类出口。
