Addictions Unit, McGill University Health Centre, Montreal, Canada.
J Subst Abuse Treat. 2010 Jan;38(1):42-50. doi: 10.1016/j.jsat.2009.06.002. Epub 2009 Jul 24.
The objectives of this prospective follow-up study were to identify factors that promote or impede the early recovery process and to examine whether drinking status at 4 weeks predicts later abstinence. Patients with alcohol use disorders were assessed by clinical and semistructured interviews upon entering addiction treatment (N = 175) and were followed up biweekly to monitor their alcohol use. During the first 4 weeks of treatment, 57% (n = 100) of patients slipped or relapsed on alcohol, whereas 43% (n = 75) were fully abstinent. Patients who slipped or relapsed were more likely to report nondependent use of a secondary substance, meet criteria for a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis II Cluster B personality disorder, have a higher level of impulsivity, and have more severe social problems at intake. The final logistic regression model accounted for 37% of the variance in drinking status. Patients who slipped or relapsed early in treatment were likely to continue to struggle to maintain abstinence at 12 weeks.
本前瞻性随访研究的目的是确定促进或阻碍早期康复过程的因素，并检验 4 周时的饮酒状态是否能预测之后的戒酒情况。入组成瘾治疗时，通过临床和半结构化访谈对患有酒精使用障碍的患者进行评估（N=175），并每两周随访一次以监测其饮酒情况。在治疗的前 4 周，57%（n=100）的患者在饮酒方面出现复发或复发，而 43%（n=75）的患者完全戒酒。复发或复发的患者更有可能报告使用次要物质的非依赖性使用，符合《精神疾病诊断与统计手册》第 4 版轴 II 群集 B 人格障碍的标准，具有更高水平的冲动性，且在入组时存在更严重的社会问题。最终的逻辑回归模型解释了饮酒状态 37%的方差。在治疗早期复发或复发的患者在 12 周时很可能继续难以保持戒酒状态。
