Department of Psychiatry, McGill University Health Centre, 1025 Pine Avenue West, Montreal, Quebec.
Can J Psychiatry. 2010 Feb;55(2):65-73. doi: 10.1177/070674371005500202.
To determine the prevalence of concurrent personality disorders (PDs) among alcoholic men and women seeking outpatient treatment, and to examine their effect on the course of alcohol treatment.
Patients with alcohol use disorders (n = 165) were assessed by clinical and semi-structured interviews, as well as self-report scales, to measure levels of psychological distress, impulsivity, social functioning, and addiction severity at treatment intake. PD diagnoses were assessed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Personality Disorder (SCID-II). Course in treatment was monitored prospectively for 12 weeks.
Using the results of the SCID-II (n = 138), the sample was divided into 3 groups-that is, no PD 41% (n = 57), Cluster B PD 32% (n = 44), and other PD 27% (n = 37). The 3 groups did not differ in their alcohol use severity at intake. However, the Cluster B PD group achieved alcohol milestones at a younger age. Subjects with a PD had more severe psychological and social problems at intake. The Cluster B PD group showed significantly higher levels of impulsivity at intake, greater likelihood of early treatment dropout, and quicker times to first slip and to relapse.
This study supports the high prevalence of concurrent PDs, particularly Cluster B PDs, among treatment-seeking alcoholics. The relation between observed high levels of impulsivity and worse course in early alcohol treatment among people with a Cluster B PD merits further investigation.
确定寻求门诊治疗的酒精中毒男女患者中同时存在人格障碍(PD)的患病率,并探讨其对酒精治疗过程的影响。
通过临床和半结构化访谈以及自我报告量表评估患有酒精使用障碍的患者(n=165),以测量治疗开始时心理困扰、冲动性、社会功能和成瘾严重程度的水平。使用《精神障碍诊断与统计手册,第四版,人格障碍的结构性临床访谈》(SCID-II)评估 PD 诊断。前瞻性监测治疗 12 周的进程。
使用 SCID-II 的结果(n=138),将样本分为 3 组,即无 PD 组 41%(n=57)、B 群 PD 组 32%(n=44)和其他 PD 组 27%(n=37)。3 组在开始时的酒精使用严重程度上没有差异。然而,B 群 PD 组达到酒精里程碑的年龄更小。有 PD 的患者在开始时存在更严重的心理和社会问题。B 群 PD 组在开始时表现出更高的冲动性水平,更早的治疗退出可能性更高,首次失误和复发的时间更快。
本研究支持在寻求治疗的酒精中毒者中同时存在 PD,特别是 B 群 PD 的高患病率。在具有 B 群 PD 的人中观察到的高冲动性水平与早期酒精治疗过程中的不良结果之间的关系值得进一步研究。