Ars2与帽结合复合体协同作用以实现基因沉默。
Ars2 and the Cap-Binding Complex Team up for Silencing.
作者信息
Nielsen Anne F, Gloggnitzer Jiradet, Martinez Javier
机构信息
Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria.
出版信息
Cell. 2009 Jul 23;138(2):224-6. doi: 10.1016/j.cell.2009.07.009.
PMID:19632172
Abstract
In this issue, Sabin et al. (2009) and Gruber et al. (2009) reveal the protein Ars2 as a versatile regulator of RNA silencing. They show that Ars2 stimulates microRNA processing, contributes to antiviral resistance in flies, and is important for cell proliferation in mammals.
摘要
在本期杂志中，萨宾等人（2009年）和格鲁伯等人（2009年）揭示了蛋白质Ars2是RNA沉默的一种多功能调节因子。他们表明，Ars2刺激微小RNA的加工，有助于果蝇的抗病毒抗性，并且对哺乳动物的细胞增殖很重要。
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