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天然Y型支架在良性气管隆突狭窄治疗中的临床应用。

Clinical application of the Natural Y stent in the management of benign carinal stenosis.

作者信息

Nam Hae-Seong, Um Sang Won, Koh Won-Jung, Suh Gee Young, Chung Man Pyo, Kwon O Jung, Kim Jhingook, Kim Hojoong

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Ann Thorac Surg. 2009 Aug;88(2):432-9. doi: 10.1016/j.athoracsur.2009.04.083.

DOI:10.1016/j.athoracsur.2009.04.083
PMID:19632389
Abstract

BACKGROUND

The Y-shaped structure of the carinal bifurcation causes difficulties in the treatment of carinal stenosis. We describe a new Y-shaped silicone stent, called the Natural Y stent. We investigated its clinical efficacy through a review of patients with benign carinal stenosis who undewent consecutive Natural Y stent placement.

METHODS

Between January 2004 and February 2008, 11 patients underwent ballooning, neodymium:yttrium-aluminum-garnet laser resection, or bougienation (by rigid bronchoscopy) to dilate the airway, followed by placement of the Natural Y stent.

RESULTS

The underlying etiologies of carinal stenosis included posttuberculosis stricture in 7 patients (64%), postintubation stenosis in 2 (18%), and postoperative malacia in 2 (18%). All patients reported subjective symptomatic relief immediately after stent placement. No procedurally related deaths or immediate major complications occurred. Stent-related late complications included granulation tissue formation (64%) and mucostasis (18%, defined as > or = 50% narrowing). The median duration of overall stent placement was 439 days (range, 119 to 1729 days). The stents were successfully removed in 4 patients (36%) after a median of 409 days.

CONCLUSIONS

The Natural Y stent provides an effective and feasible therapeutic modality in patients with benign carinal stenosis, with or without previous thoracic airway interventions.

摘要

背景

气管隆突分叉处的Y形结构给气管隆突狭窄的治疗带来困难。我们描述了一种新型的Y形硅胶支架,称为自然Y支架。我们通过回顾连续接受自然Y支架置入术的良性气管隆突狭窄患者来研究其临床疗效。

方法

2004年1月至2008年2月期间,11例患者接受了球囊扩张、钕:钇铝石榴石激光切除或(通过硬支气管镜)探条扩张气道,随后置入自然Y支架。

结果

气管隆突狭窄的潜在病因包括7例(64%)结核后狭窄、2例(18%)插管后狭窄和2例(18%)术后软化。所有患者在支架置入后均立即报告主观症状缓解。未发生与手术相关的死亡或即刻严重并发症。与支架相关的晚期并发症包括肉芽组织形成(64%)和黏液潴留(18%,定义为狭窄≥50%)。支架置入的总中位持续时间为439天(范围119至1729天)。4例患者(36%)在中位409天后成功取出支架。

结论

自然Y支架为良性气管隆突狭窄患者提供了一种有效且可行的治疗方式,无论患者之前是否接受过胸段气道干预。

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