Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
J Am Acad Dermatol. 2010 Jan;62(1):139-141. doi: 10.1016/j.jaad.2009.01.031. Epub 2009 Jul 25.
Follicular mucinosis is an uncommon inflammatory disorder characterized histologically by mucin accumulation in the follicular epithelium. The condition is generally divided into primary and secondary forms, the latter being frequently associated with mycosis fungoides. Lesional skin T-cell clonality has been documented in some patients with follicular mucinosis, even those with no histologic evidence of cutaneous lymphoma. In this report, we describe a patient with clonal idiopathic primary follicular mucinosis who had complete clinical, histologic, and molecular remission with minocycline therapy.
滤泡黏液病是一种罕见的炎症性疾病，组织学上表现为滤泡上皮内黏蛋白积聚。该疾病通常分为原发性和继发性，后者常与蕈样真菌病相关。一些滤泡黏液病患者的皮损 T 细胞克隆性已被记录，即使那些没有皮肤淋巴瘤组织学证据的患者也是如此。在本报告中，我们描述了一例原发性特发性滤泡黏液病的患者，其使用米诺环素治疗后达到了完全的临床、组织学和分子缓解。
