5-氟尿嘧啶致急性精神病 1 例。
A case of 5-fluorouracil-induced acute psychosis.
机构信息
Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
出版信息
Clin Colorectal Cancer. 2009 Jul;8(3):166-8. doi: 10.3816/CCC.2009.n.027.
PMID:19632932
Abstract
5-Fluorouracil (5-FU) is a chemotherapeutic agent commonly used in a number of solid malignancies, including colorectal cancer. Herein, we report the first case of 5-FU-induced psychosis. Psychosis occurred after the first 2 cycles of 5-FU, oxaliplatin, leucovorin, plus bevacizumab and recurred upon rechallenge with further 5-FU and leucovorin.
摘要
5-氟尿嘧啶（5-FU）是一种常用于多种实体恶性肿瘤的化疗药物，包括结直肠癌。本文报告了首例 5-FU 诱导的精神症状。精神症状发生在接受 5-FU、奥沙利铂、亚叶酸钙和贝伐珠单抗的前 2 个周期后，再次使用 5-FU 和亚叶酸钙时复发。
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