一名患有广泛耐药结核病的幼儿的长期利奈唑胺治疗
Long-term linezolid treatment in a young child with extensively drug-resistant tuberculosis.
作者信息
Schaaf H Simon, Willemse Marianne, Donald Peter R
机构信息
Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children's Hospital, Cape Town, South Africa.
出版信息
Pediatr Infect Dis J. 2009 Aug;28(8):748-50. doi: 10.1097/INF.0b013e31819bc491.
PMID:19633523
Abstract
Treatment of extensively drug-resistant tuberculosis (XDR-TB) is a challenge. We describe a young child with pulmonary XDR-TB who did not respond to an aggressive multidrug-resistant TB treatment regimen, but was cured with linezolid in combination with other reserve antituberculous drugs. No serious adverse events were observed during 19 months of treatment for XDR-TB.
摘要
广泛耐药结核病（XDR-TB）的治疗是一项挑战。我们描述了一名患有肺部XDR-TB的幼儿，其对积极的耐多药结核病治疗方案无反应，但通过利奈唑胺联合其他备用抗结核药物治愈。在XDR-TB的19个月治疗期间未观察到严重不良事件。
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