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利奈唑胺治疗儿童耐多药/广泛耐药结核病：一家儿童传染病科的经验

Linezolid in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis in paediatric patients: experience of a paediatric infectious diseases unit.

作者信息

Kjöllerström Paula, Brito Maria João, Gouveia Catarina, Ferreira Gonçalo, Varandas Luís

机构信息

Department of Paediatrics, Infectious Diseases, Hospital Dona Estefânia, Lisbon, Portugal.

出版信息

Scand J Infect Dis. 2011 Jul;43(6-7):556-9. doi: 10.3109/00365548.2011.564649. Epub 2011 Mar 10.

DOI:10.3109/00365548.2011.564649
PMID:21391771
Abstract

Linezolid has been used in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis in adults with encouraging results, however experience in children is scarce. We describe our experience with the use of linezolid as part of a multidrug regimen in the treatment of 4 patients who had persistent positive cultures, despite prolonged combined therapy.

摘要

利奈唑胺已被用于治疗成人耐多药/广泛耐药结核病，效果令人鼓舞，但儿童用药经验较少。我们描述了在4例尽管接受了长期联合治疗但培养结果仍持续呈阳性的患者中，将利奈唑胺作为多药治疗方案的一部分使用的经验。

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