Bayer Otmar, Neuhauser Hannelore, von Kries Rüdiger
Institute for Social Paediatrics and Adolescent Medicine, Ludwig-Maximilians University, Munich, Germany.
J Hypertens. 2009 Sep;27(9):1789-93. doi: 10.1097/HJH.0b013e32832e49ef.
Short sleep duration as a risk factor for higher blood pressure has been reported by several studies on adults. This study aimed to investigate this association in children, considering age-specific effects and distributional aspects.
Using data from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS, 2003-2006), information on daily sleeping hours and blood pressure measurements was available for 7701 children between 3 and 10 years of age.
Using an age-independent measure for sleep duration, linear regression revealed a -0.80 mmHg (95% confidence interval -1.39; -0.22) mean arterial pressure difference between the children with the longest vs. shortest sleep duration. This effect was independent of age and was no longer significant when adjusted for BMI z-score and reported physical activity. Effect estimates obtained from quantile regression confirmed lack of significant associations over the entire blood pressure distribution.
Sleep duration showed no or only marginal association with blood pressure in this large sample of children between 3 and 10 years of age. Further analysis indicated no age dependency or certain groups (e.g. prehypertensive children), in which sleep duration showed a greater effect on blood pressure.
多项针对成年人的研究报告称,睡眠时长较短是血压升高的一个风险因素。本研究旨在探讨儿童中的这种关联,同时考虑年龄特异性效应和分布方面的因素。
利用德国儿童和青少年健康访谈与检查调查(KiGGS,2003 - 2006年)的数据,可获取7701名3至10岁儿童的每日睡眠时间信息和血压测量值。
使用与年龄无关的睡眠时长测量方法,线性回归显示,睡眠时长最长与最短的儿童之间,平均动脉压差值为 -0.80 mmHg(95%置信区间 -1.39;-0.22)。这种效应与年龄无关,在根据BMI z评分和报告的身体活动进行调整后不再显著。从分位数回归获得的效应估计值证实,在整个血压分布范围内缺乏显著关联。
在这个包含3至10岁儿童的大样本中,睡眠时长与血压之间无关联或仅有微弱关联。进一步分析表明不存在年龄依赖性,也没有特定群体(例如高血压前期儿童),在这些群体中睡眠时长对血压有更大影响。