外阴癌和宫颈癌患者中人类乳头瘤病毒6型和16型DNA序列的研究。
Study of sequences of DNA of the human papilloma virus genotypes 6 and 16 in patients with cancer of vulva and cervix uteri.
作者信息
Bokhman J V, Kuznetsov O K, Maximov S J, Tadzhibayeva J T, Aron P A, Vasilyev B V, Migunova B V, Tkeshmelashvili V G
机构信息
Petròv Research Institute of Oncology, USSR Ministry of Health, Leningrad.
出版信息
Clin Exp Obstet Gynecol. 1990;17(3-4):117-20.
PMID:1963384
Abstract
Puntaction hybridization method was used to determine the incidence of the human papilloma virus infection in cases with the squamous cell cancer of the vulva and cervix uteri. The presence of sequences of DNA of the HPV genotype and 16 was found in 74.2% of cases, which points to a suspicion for the involvement of the above viruses in etiology of cervix uteri cancer, as well as vulva cancer.
摘要
采用点杂交法测定外阴和子宫颈鳞状细胞癌患者人乳头瘤病毒感染的发生率。在74.2%的病例中发现了HPV 16型基因型的DNA序列，这表明怀疑上述病毒参与子宫颈癌以及外阴癌的病因。
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