Saggar Rajan, Saggar Rajeev, Aboulhosn Jamil, Belperio John A, Zisman David A, Lynch Joseph P
Division of Pulmonary, Critical Care Medicine, and Hospitalists, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-1690, USA.
Semin Respir Crit Care Med. 2009 Aug;30(4):399-410. doi: 10.1055/s-0029-1233309. Epub 2009 Jul 24.
Pulmonary hypertension (PH) can occur as either a primary or a secondary process, and in general, its presence increases overall morbidity and mortality. Importantly, the majority of prior studies have been in the setting of idiopathic pulmonary arterial hypertension (IPAH); thus the following discussion focuses on IPAH. Because the majority of available diagnostic strategies lack sensitivity and specificity, the physician must maintain a high index of suspicion in considering PAH. This article provides an overview of the available diagnostic studies for PAH with a particular focus on hemodynamic assessment. Novel approaches to the often delayed diagnosis of PAH are being studied and are also discussed here.
肺动脉高压（PH）可作为原发性或继发性疾病出现，总体而言，其存在会增加总体发病率和死亡率。重要的是，大多数先前的研究都是针对特发性肺动脉高压（IPAH）进行的；因此，以下讨论将聚焦于IPAH。由于大多数现有的诊断策略缺乏敏感性和特异性，医生在考虑PAH时必须保持高度的怀疑指数。本文概述了PAH可用的诊断研究，特别关注血流动力学评估。针对PAH常被延迟诊断的新方法正在研究中，本文也将进行讨论。
