Ipser Jonathan C, Stein Dan J
Department of Psychiatry and Mental Health, University of Cape Town, Groote Schuur Hospital, Anzio Road, Observatory, Cape Town, South Africa.
Curr Psychiatry Rep. 2009 Aug;11(4):302-9. doi: 10.1007/s11920-009-0044-7.
Meta-analyses are seen as representing the pinnacle of a hierarchy of evidence used to inform clinical practice. Therefore, the potential importance of differences in the rigor with which they are conducted and reported warrants consideration. In this review, we use standardized instruments to describe the scientific and reporting quality of meta-analyses of randomized controlled trials of the treatment of anxiety disorders. We also use traditional and novel metrics of article impact to assess the influence of meta-analyses across a range of research fields in the anxiety disorders. Overall, although the meta-analyses that we examined had some flaws, their quality of reporting was generally acceptable. Neither the scientific nor reporting quality of the meta-analyses was predicted by any of the impact metrics. The finding that treatment meta-analyses were cited less frequently than quantitative reviews of studies in current "hot spots" of research (ie, genetics, imaging) points to the multifactorial nature of citation patterns. A list of the meta-analyses included in this review is available on an evidence-based website of anxiety and trauma-related disorders.
元分析被视为用于指导临床实践的证据等级体系的巅峰。因此,其开展和报告的严谨程度差异的潜在重要性值得考虑。在本综述中,我们使用标准化工具来描述焦虑症治疗随机对照试验元分析的科学质量和报告质量。我们还使用传统和新颖的文章影响力指标来评估元分析在焦虑症一系列研究领域中的影响。总体而言,尽管我们审查的元分析存在一些缺陷,但其报告质量总体上是可以接受的。元分析的科学质量和报告质量均未被任何影响力指标所预测。治疗元分析的被引频次低于当前研究“热点”(即遗传学、影像学)中研究的定量综述,这一发现表明了引文模式的多因素性质。本综述中纳入的元分析列表可在一个基于证据的焦虑和创伤相关障碍网站上获取
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