中国中部和东南部地区人粒细胞无形体病的血清流行率。
Seroprevalence of human granulocytotropic anaplasmosis in central and southeastern China.
作者信息
Zhang Shouyin, Hai Rong, Li Wenyuan, Li Guohua, Lin Guangyu, He Jinrong, Fu Xiuping, Zhang Jingshan, Cai Hong, Ma Fengqin, Zhang Jianhua, Yu Dongzheng, Yu Xue-Jie
机构信息
State Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China.
出版信息
Am J Trop Med Hyg. 2009 Aug;81(2):293-5.
Human granulocytic anaplasmosis (HGA) is an emerging tick-borne infectious disease. To determine the prevalence of HGA in central and southeastern China, a total of 323 human sera were collected from individuals at high risk for exposure to ticks and animals. The IgG antibody against the etiologic agent of HGA, Anaplasma phagocytophilum was detected with indirect immunofluorescence assay. The results showed that 20% of the tested individuals (64/323) were positive to A. phagocytophilum and that the incidence was higher in male (22%) than female (16%). We concluded that A. phagocytophilum infection was prevalent in central and southeastern China.
人粒细胞无形体病（HGA）是一种新出现的蜱传传染病。为确定中国中部和东南部地区HGA的流行情况，共采集了323份来自有蜱虫和动物接触高风险个体的人血清。采用间接免疫荧光法检测针对HGA病原体嗜吞噬细胞无形体的IgG抗体。结果显示，20%（64/323）的受测个体对嗜吞噬细胞无形体呈阳性反应，男性发病率（22%）高于女性（16%）。我们得出结论，嗜吞噬细胞无形体感染在中国中部和东南部地区较为普遍。
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