Sánchez Ricardo, Pantoja-Uceda David, Torres Daniel, Prieto Jesús, Campos-Olivas Ramón, Blanco Francisco J
Structural Biology Unit, CIC Biogune, Parque Tecnológico de Bizkaia, Ed. 800, Derio, 48160, Spain.
Biomol NMR Assign. 2008 Dec;2(2):139-42. doi: 10.1007/s12104-008-9105-9. Epub 2008 Aug 12.
Gadd45 alpha is a predominantly nuclear protein encoded by a DNA-damage-inducible gene which is transcriptionally regulated by the tumor suppressor p53. The interactions of Gadd45 alpha with several other proteins play a central role in DNA repair, cell cycle control and apoptosis. The NMR assignments of human Gadd45 alpha protein reported here provide the basis for further characterization of these interactions.
