Dangubić V, Ponomarev D, Aćimović S, Cirić B, Berger A
Institut za radiologiju, Vojnomedicinska Akademija, Klinika za plućne bolesti.
Vojnosanit Pregl. 1990 Nov-Dec;47(6):414-8.
Within the five-year period (1984-1988) the oat cell bronchogenic carcinoma was diagnosed and treated in 151 patients. Analysed were 74 patients having received complete treatment. Patients with disseminated form received only polychemotherapy in 6 cycles (cyclophosphamide, doxorubicin, vincristine and etoposide) and those with limited disease also received additional, local-regional radiotherapy of 45-50 Gy. In complete respondents preventive brain irradiation was applied. In selected patients with initial forms of the disease surgical resection with additional polychemotherapy were applied. The best survival showed respondents with limited disease and operated patients. Average survival of the whole group was 72 weeks. One year survived 31 out of 74 (41.9%) patients and two years survived 10 out of 74 (13.5%) patients.
在五年期间(1984 - 1988年),151例患者被诊断并接受了燕麦细胞支气管源性癌的治疗。对74例接受了完整治疗的患者进行了分析。播散型患者仅接受了6个周期的多药化疗(环磷酰胺、阿霉素、长春新碱和依托泊苷),局限性疾病患者还接受了45 - 50 Gy的额外局部区域放疗。对完全缓解者进行了预防性脑照射。对部分初始疾病形式的患者采用了手术切除加额外多药化疗的方法。局限性疾病患者和接受手术的患者生存率最佳。整个组的平均生存期为72周。74例患者中31例(41.9%)存活1年,74例患者中10例(13.5%)存活2年。