Pace Wilson D, Cifuentes Maribel, Valuck Robert J, Staton Elizabeth W, Brandt Elias C, West David R
University of Colorado Denver, School of Medicine, Aurora, Colorado 80045-0508, USA.
Ann Intern Med. 2009 Sep 1;151(5):338-40. doi: 10.7326/0003-4819-151-5-200909010-00140. Epub 2009 Jul 28.
The Distributed Ambulatory Research in Therapeutics Network (DARTNet) is a federated network of electronic health data from 8 organizations representing more than 500 clinicians and more than 400 000 patients. DARTNet was designed to increase knowledge of the comparative effectiveness of prescription medications and medical devices. Traditional observational comparative effectiveness research is conducted using large data sets, such as claims databases. Such databases do not provide important clinical information that is critical to understanding comparative effectiveness. By linking electronic health records, laboratory and imaging data, and administrative data from diverse and geographically disparate patients, DARTNet provides important new insight into the comparative effectiveness of oral diabetes medications, and it is ready for expansion to further enable effectiveness research.
治疗网络分布式门诊研究（DARTNet）是一个联合网络，整合了来自8个机构的电子健康数据，涵盖500多名临床医生和40多万名患者。DARTNet旨在增进对处方药和医疗设备相对疗效的了解。传统的观察性相对疗效研究使用大型数据集，如理赔数据库。此类数据库无法提供对于理解相对疗效至关重要的重要临床信息。通过连接电子健康记录、实验室和影像数据以及来自不同地区患者的管理数据，DARTNet为口服糖尿病药物的相对疗效提供了重要的新见解，并且已准备好进行扩展以进一步推动疗效研究。
