Wilson J H, Hermann-Dekkers W M, Leemans-Dessy S, Meijer J W
Vet Rec. 1977 Jun 25;100(26):552-4. doi: 10.1136/vr.100.26.552.
A fluid adjuvanted vaccine consisting of inactivated hepatitis virus (iH) and leptospirae antigens (L) was developed. The vaccine (Kavak iHL; Duphar) was tested in several vaccination programmes both alone and in combination with freeze dried measles (M) or distemper (D) vaccines. The results demonstrate that this new vaccine is also effective in pups with maternally derived antibodies, although a second vaccination at 14 weeks of age is recommended to boost the first vaccination. For the booster vaccination either the iHL-vaccine or the liver attenuated hepatitis vaccine (H) can be used.
研发出了一种由灭活肝炎病毒（iH）和钩端螺旋体抗原（L）组成的含佐剂液体疫苗。该疫苗（Kavak iHL；杜法尔公司）在多个疫苗接种计划中单独以及与冻干麻疹（M）或犬瘟热（D）疫苗联合进行了测试。结果表明，这种新疫苗对有母源抗体的幼犬也有效，不过建议在14周龄时进行第二次接种以加强首次接种。加强接种时可以使用iHL疫苗或肝脏减毒肝炎疫苗（H）。
