Gaulier A, Lucas G, Ronco P
Department of Pathology, Hospital Victor Dupouy, Argenteuil, France.
Histopathology. 1990 Nov;17(5):451-5. doi: 10.1111/j.1365-2559.1990.tb00767.x.
The clinical presentation of cervical metastases in a young woman presenting with cervical lymphadenopathy is described. The clinical, histological, ultrastructural and immunological findings establishing the diagnosis of a renal primary tumour are seen. The significance of mixed tumour cell expression of antigens specific for the proximal tubule (CD10, DPP4 and aminopeptidase N) and of Tamm Horsfall protein, normally expressed on the thick ascending limb of loop of Henle and distal tubule, is discussed.
描述了一名出现颈部淋巴结病的年轻女性颈部转移瘤的临床表现。展示了确立肾原发性肿瘤诊断的临床、组织学、超微结构和免疫学检查结果。讨论了近端小管特异性抗原（CD10、DPP4和氨肽酶N）以及通常在髓袢升支粗段和远曲小管表达的Tamm Horsfall蛋白的混合肿瘤细胞表达的意义。
