Yamashiro K, Suzuki H, Nagayo T
Virchows Arch A Pathol Anat Histol. 1977 Jul 11;374(4):275-84. doi: 10.1007/BF00432651.
The signet-ring cells seen in gastric carcinoma of the diffuse type were studied by light and electron microscopy. A classification of these cells into Types A, B and C was developed, based on intracellular mucous granules, nuclei and organelles, and be reactions to PAS and Alcian-blue staining. The gradual transition of type A cells to Type B and the subsequent change of Type B to Type C suggest successive stages in maturation. These cells, especially those of Type B, resemble the mucous neck cells of the corpus and the glands of the pylorus.
对弥漫型胃癌中所见的印戒细胞进行了光镜和电镜研究。根据细胞内黏液颗粒、细胞核和细胞器以及对PAS和阿尔辛蓝染色的反应，将这些细胞分为A、B、C三型。A型细胞向B型的逐渐转变以及随后B型向C型的变化提示了成熟过程中的连续阶段。这些细胞，尤其是B型细胞，类似于胃体的黏液颈细胞和幽门腺。
