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预测颞下颌关节紊乱症患者物理医学治疗的结果。

Predicting the outcome of a physical medicine treatment for temporomandibular disorder patients.

作者信息

Clark Glenn T, Baba Kazuyoshi, McCreary Charles P

机构信息

School of Dentistry, University of Southern California, Los Angeles, CA, USA.

出版信息

J Orofac Pain. 2009 Summer;23(3):221-9.

Abstract

AIMS

To investigate whether any of the pretreatment physical signs, symptoms, and responses on psychological questionnaires would predict treatment outcomes after a standardized temporomandibular disorder (TMD) treatment program.

METHODS

The care provided to 157 TMD patients was a short course of physical therapy, an occlusal appliance, and over-the-counter nonsteroidal anti-inflammatory drugs (OTC NSAIDs). A multidimensional outcome assessment was performed using six variables. Follow-up data were available on 81.5% of enrolled subjects and elapsed time from initial visit to the two follow-up points was 13 +/- 4.7 and 33.6 +/- 9.8 months, respectively. Multiple regression analyses were conducted to assess the relationship between 18 predictor variables and the six outcome variables.

RESULTS

The results showed that the combination of a higher initial visual analog scale (VAS) pain score plus a lower jaw function interference score was significantly associated with a reduction of VAS pain after treatment (P < .05; adjusted R2 = 0.54). Moreover, the combination of a higher initial activity limitation score plus a lower jaw function interference score was associated with a greater reduction of the activity limitation score after treatment (P < .05; adjusted R2 = 0.36). None of the other outcomes were found to relate to any of the pretreatment variables. It must be noted that no single variable was a strong predictor and the odds ratios between the above three variables and the predicted outcomes were not robust.

CONCLUSION

The corollary of these results suggests that if a high degree of jaw function interference is present (eg, clicking, locking), then the prognosis of improvement with brief self-directed physical therapy, an occlusal appliance, and OTC NSAID is lower, at least within the time frame of this study.

摘要

目的

探讨在标准化颞下颌关节紊乱病(TMD)治疗方案后,治疗前的任何体征、症状以及心理问卷反应是否能预测治疗结果。

方法

为157例TMD患者提供的治疗包括短期物理治疗、咬合器以及非处方非甾体抗炎药(OTC NSAIDs)。使用六个变量进行多维度结果评估。81.5%的入组受试者有随访数据,从初次就诊到两个随访点的时间间隔分别为13±4.7个月和33.6±9.8个月。进行多元回归分析以评估18个预测变量与六个结果变量之间的关系。

结果

结果显示,较高的初始视觉模拟量表(VAS)疼痛评分加上较低的下颌功能干扰评分的组合与治疗后VAS疼痛的减轻显著相关(P <.05;调整后的R2 = 0.54)。此外,较高的初始活动受限评分加上较低的下颌功能干扰评分的组合与治疗后活动受限评分的更大降低相关(P <.05;调整后的R2 = 0.36)。未发现其他结果与任何治疗前变量有关。必须指出的是,没有单个变量是强有力的预测因素,上述三个变量与预测结果之间的优势比并不稳健。

结论

这些结果的推论表明,如果存在高度的下颌功能干扰(例如,弹响、绞锁),那么采用简短的自我指导物理治疗、咬合器和OTC NSAID进行改善的预后较低,至少在本研究的时间范围内如此。

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