Xu Qiang, Li Jing, Wang Chi, Hu Sun-Qiang, Chen Yin, Nie Xin, Xiao Jin
Department of Oral Maxillofacial Surgery, School and Hospital of Stomatology, Wenzhou Medical University, No. 1288 Longyao Avenue, Longwan District, Wenzhou, 325000, Zhejiang, China.
BMC Oral Health. 2024 Jul 16;24(1):802. doi: 10.1186/s12903-024-04572-4.
Few studies have been conducted on treating temporomandibular disorders (TMDs) with new digital occlusal splints, which has increasingly attracted wide attention.
To evaluate the clinical efficacy and quality of life (QoL) of Kovacs digital occlusal splint (KDOS) treatment in patients with TMD.
Eighty-nine patients with TMD who were treated using KDOS were analyzed. The patients were divided into three groups according to the Wilkes stage. The clinical symptoms and QoL scores of the patients in each group were recorded before and at least three months after treatment, and the data were statistically analyzed and compared. The relationships between the disease severity, sex, age, and level of QoL before treatment and improvement in the clinical symptoms were analyzed using binary logistic regression.
The mean age and follow-up period of the patients were 28.0 ± 10.4 years and 4.9 ± 2.1 months, respectively. After KDOS treatment, the improvement rates of joint noise and pain were 80.4% and 69.8%, respectively. Additionally, the patients' maximum mouth opening and global QoL mean scores significantly improved compared to those before treatment (p < 0.001). Binary logistic regression analysis revealed that the factors affecting the improvement in the clinical symptoms were disease severity and level of QoL before treatment.
KDOS can improve the clinical symptoms and QoL of patients with TMD. Moreover, patients without osteoarthritis and with low pretreatment QoL levels are more likely to demonstrate clinical improvement.
The trial was registered with Chinese Clinical Trial Registry (ChiCTR) (ID: ChiCTR2300076518) on 11/10/2023.
关于新型数字牙合垫治疗颞下颌关节紊乱病（TMDs）的研究较少，这一治疗方法日益受到广泛关注。
评估科瓦克斯数字牙合垫（KDOS）治疗TMD患者的临床疗效和生活质量（QoL）。
分析89例使用KDOS治疗的TMD患者。根据威尔克斯分期将患者分为三组。记录每组患者治疗前及治疗后至少三个月的临床症状和QoL评分，并对数据进行统计学分析和比较。采用二元逻辑回归分析疾病严重程度、性别、年龄和治疗前QoL水平与临床症状改善之间的关系。
患者的平均年龄和随访时间分别为28.0±10.4岁和4.9±2.1个月。KDOS治疗后，关节弹响和疼痛的改善率分别为80.4%和69.8%。此外，与治疗前相比，患者的最大开口度和整体QoL平均评分显著提高（p<0.001）。二元逻辑回归分析显示，影响临床症状改善的因素为疾病严重程度和治疗前QoL水平。
KDOS可改善TMD患者的临床症状和QoL。此外，无骨关节炎且治疗前QoL水平较低的患者更有可能出现临床改善。
该试验于2023年10月11日在中国临床试验注册中心（ChiCTR）注册（注册号：ChiCTR2300076518）。
