Carret A S, Loriette Y, Bezou M J, Rousseau P, Chassagne J, Demeocq F, Malpuech G
Service de pédiatrie B, Hôtel-Dieu, Clermont-Ferrand, France.
Pediatrie. 1990;45(12):845-8.
An 11 year-old boy was treated for acute promyelocytic leukemia (ALM3) with chemotherapy according to the LAME 86 protocol (aracytin and rubidomycin). The first complete remission was consolidated by two autologous bone marrow transplantations. Following autologous graft, a persistent thrombocytopenic purpura appeared. Autoimmune origin was indicated by a decrease in platelet survival time and by the presence of high levels of antiplatelet antibodies.
一名11岁男孩按照LAME 86方案（阿糖胞苷和柔红霉素）接受化疗治疗急性早幼粒细胞白血病（ALM3）。首次完全缓解通过两次自体骨髓移植得以巩固。自体移植后，出现了持续性血小板减少性紫癜。血小板存活时间缩短以及高水平抗血小板抗体的存在提示为自身免疫性病因。
