Iakhno N N, Bashlykov N A, Gribunov Iu P, Peskov D Iu
Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(11):124-8.
Metastatic injury to the brain occurs very rarely in reticulosarcoma patients, presenting considerable difficulties for clinical diagnosis. Such an injury has not been reported in the neurological literature. The authors describe a case of the generalized form of reticulosarcoma with multiple metastases and secondary hemorrhages to the brain attended by blood breakthrough to the ventricular system. Difficulties are noted, occurring in differential diagnosis, and specific features of the clinical picture and pathomorphological alterations are described. In contrast to the primarily hemorrhagic manifestations in the brain, blastomatous proliferation in the visceral system (the gastrointestinal tract, lymph nodes) provoked appreciable necrotic lesions.
网状细胞肉瘤患者发生脑转移损伤极为罕见,给临床诊断带来了相当大的困难。神经学文献中尚未报道过此类损伤。作者描述了一例全身性网状细胞肉瘤伴多发转移及脑继发性出血并伴有血液破入脑室系统的病例。文中指出了鉴别诊断中存在的困难,并描述了临床表现和病理形态学改变的具体特征。与脑内主要的出血表现不同,内脏系统(胃肠道、淋巴结)的母细胞瘤样增殖引发了明显的坏死性病变。