Liu Yi-Wen, Neely Stephen T
Boys Town National Research Hospital, 555 North 30th Street, Omaha, NE 68131, USA.
J Acoust Soc Am. 2009 Aug;126(2):751-61. doi: 10.1121/1.3158919.
A nonlinear piezoelectric circuit is proposed to model electromechanical properties of the outer hair cell (OHC) in mammalian cochleae. The circuit model predicts (a) that the nonlinear capacitance decreases as the stiffness of the load increases, and (b) that the axial compliance of the cell reaches a maximum at the same membrane potential for peak capacitance. The model was also designed to be integrated into macro-mechanical models to simulate cochlear wave propagation. Analytic expressions of the cochlear-partition shunt admittance and the wave propagation function are derived in terms of OHC electro-mechanical parameters. Small-signal analyses indicate that, to achieve cochlear amplification, (1) nonlinear capacitance must be sufficiently high and (2) the OHC receptor current must be sensitive to the velocity of the reticular lamina.
提出了一种非线性压电电路，用于模拟哺乳动物耳蜗外毛细胞（OHC）的机电特性。该电路模型预测：（a）随着负载刚度增加，非线性电容减小；（b）在峰值电容的相同膜电位下，细胞的轴向顺应性达到最大值。该模型还设计为可集成到宏观力学模型中，以模拟耳蜗波传播。根据OHC机电参数，推导了耳蜗分区并联导纳和波传播函数的解析表达式。小信号分析表明，为实现耳蜗放大，（1）非线性电容必须足够高；（2）OHC受体电流必须对网状板的速度敏感。
