Gerber Linda M, Ni Quanhong, Härtl Roger, Ghajar Jamshid
Department of Public Health, Weill Cornell Medical College, New York, USA.
J Trauma Manag Outcomes. 2009 Jul 30;3:9. doi: 10.1186/1752-2897-3-9.
The causes of severe traumatic brain injury (TBI) vary by age and other demographic characteristics. Mortality after trauma is higher for elderly than younger patients. This study is based on 2779 patients with severe TBI treated at 24 trauma centers enrolled in a New York State quality improvement program. The prospectively collected database includes information on age, sex, mechanism of injury, initial Glasgow Coma Scale score, blood pressure, pupillary assessment, and CT scan findings. This multi-center study was conducted to explore the impact of falls on early mortality from severe TBI among the elderly.
After exclusion criteria were applied, a total of 2162 patients were eligible for analysis. Falls contributed to 21% of all severe TBI, 12% occurring from > 3 meters and 9% from < 3 meters. Two-week mortality ranged from 18% due to injuries other than falls to 31% due to falls from < 3 meters (p =< 0.0001). Mortality after a severe TBI is much greater among older people, reaching 58% for people 65 years and older sustaining a fall from < 3 meters.
Among those 65 and older, falls contributed to 61% of all injuries and resulted in especially high mortality among individuals experiencing low falls. Preventive efforts directed toward older people to avoid falls from < 3 meters could have a significant impact on mortality.
重度创伤性脑损伤(TBI)的病因因年龄和其他人口统计学特征而异。创伤后的死亡率在老年人中高于年轻患者。本研究基于在纽约州质量改进项目中登记的24个创伤中心治疗的2779例重度TBI患者。前瞻性收集的数据库包括年龄、性别、损伤机制、初始格拉斯哥昏迷量表评分、血压、瞳孔评估和CT扫描结果等信息。这项多中心研究旨在探讨跌倒对老年人重度TBI早期死亡率的影响。
应用排除标准后,共有2162例患者符合分析条件。跌倒导致的重度TBI占所有病例的21%,其中12%发生于3米以上高度的跌倒,9%发生于3米及以下高度的跌倒。两周死亡率从非跌倒损伤所致的18%到3米及以下高度跌倒所致的31%不等(p≤0.0001)。重度TBI后的死亡率在老年人中更高,65岁及以上因3米及以下高度跌倒的患者死亡率达到58%。
在65岁及以上人群中,跌倒导致的损伤占所有损伤的61%,且在低度跌倒者中导致特别高的死亡率。针对老年人采取预防措施以避免3米及以下高度的跌倒可能会对死亡率产生重大影响。