Strelets V B
Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 Sep-Oct;40(5):897-902.
In the paper possible neurophysiological mechanisms are described which are the basis of formation of inadequately coloured negative emotions and of disturbance of cognitive function in patients with depressive syndrome within maniac-depressive psychosis and schizophrenia. Analysis of interconnection between posterior brain regions where sensory information comes in, and anterior regions where evaluation of the incoming information takes place, has shown that in the moment of emotions formation and fulfillment of the task of reaction choice from three alternatives between these parts "transversal functional block" is revealed mainly in the left hemisphere what is manifested in phase shifts of the evoked potential waves. This block may be the basis of disturbance of normal exchange of impulse activity between them and in its turn prevent formation of adequately coloured emotions and realization of normal cognitive function. On the basis of the present study a method is proposed which includes medical electric stimulation, in response to which a quick response activity of the patient is required, based on reaction choice from three alternatives. This method promotes weakening of the functional block and improvement of clinic state of patients with depressive syndrome.
本文描述了可能的神经生理机制，这些机制是躁狂抑郁症和精神分裂症患者抑郁综合征中形成颜色不适当的负面情绪以及认知功能障碍的基础。对接收感觉信息的后脑区域与对传入信息进行评估的前脑区域之间的相互联系进行分析后发现，在情绪形成以及从三种选择中做出反应选择任务执行的时刻，主要在左半球发现了“横向功能阻滞”，这表现为诱发电位波的相位偏移。这种阻滞可能是它们之间正常冲动活动交换受到干扰的基础，进而阻止了颜色适当的情绪形成以及正常认知功能的实现。基于本研究，提出了一种方法，该方法包括医学电刺激，对此需要患者基于从三种选择中做出反应选择进行快速反应活动。该方法有助于减弱功能阻滞并改善抑郁综合征患者的临床状态。
