Bourquin T, Schoeffter F, Duri A, Guihard P, Pellerin F
Laboratoire de Contrôle de Qualité, Coopération Pharmaceutique Française, Melun.
Ann Pharm Fr. 1990;48(4):173-84.
The control of oils and fats requires analytical processes far surpassing the traditional framework of physical properties and chemical characteristics. The control of cod liver oil is improved by the use of these procedures. The present report is devoted to the measurement of vitamin A by ultraviolet spectrophotometry and of vitamin D3 by high performance liquid chromatography, to the determination of the profile of their fatty acids and polyunsaturated fats, as well as to their measurement by liquid gas chromatography after derivatisation. The results permit the definition of the cod liver oil's quality, the differentiation between fish oils and the detection of possible changes. A technique for verifying the absence of butylhydroxyanisol and of butylhydroxytoluen is also described.
油脂的控制需要远超传统物理性质和化学特性框架的分析过程。通过使用这些程序，鱼肝油的控制得到了改善。本报告致力于通过紫外分光光度法测定维生素A，通过高效液相色谱法测定维生素D3，测定其脂肪酸和多不饱和脂肪的谱图，以及在衍生化后通过液相气相色谱法进行测定。这些结果有助于定义鱼肝油的质量，区分鱼油并检测可能的变化。还描述了一种验证不存在丁基羟基茴香醚和丁基羟基甲苯的技术。
