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一种用于荧光分子断层成像的基于小波的多分辨率重建方法。

A wavelet-based multiresolution reconstruction method for fluorescent molecular tomography.

作者信息

Zou Wei, Wang Jiajun, Wu Kongpei, Feng David Dagan

机构信息

School of Electronics and Information Engineering, Soochow University, Suzhou 215021, China.

出版信息

Int J Biomed Imaging. 2009;2009:294545. doi: 10.1155/2009/294545. Epub 2009 Jul 22.

DOI:10.1155/2009/294545
PMID:19644557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2715901/
Abstract

Image reconstruction of fluorescent molecular tomography (FMT) often involves repeatedly solving large-dimensional matrix equations, which are computationally expensive, especially for the case where there are large deviations in the optical properties between the target and the reference medium. In this paper, a wavelet-based multiresolution reconstruction approach is proposed for the FMT reconstruction in combination with a parallel forward computing strategy, in which both the forward and the inverse problems of FMT are solved in the wavelet domain. Simulation results demonstrate that the proposed approach can significantly speed up the reconstruction process and improve the image quality of FMT.

摘要

荧光分子断层成像(FMT)的图像重建通常涉及反复求解大型矩阵方程,这在计算上代价高昂,特别是在目标与参考介质的光学特性存在较大偏差的情况下。本文提出了一种基于小波的多分辨率重建方法,结合并行正向计算策略用于FMT重建,其中FMT的正向和逆向问题均在小波域中求解。仿真结果表明,该方法能够显著加快重建过程并提高FMT的图像质量。

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本文引用的文献

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Fluorescent molecular tomographic image reconstruction based on the Green's function.基于格林函数的荧光分子断层图像重建
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Combined diffuse optical tomography (DOT) and MRI system for cancer imaging in small animals.用于小动物癌症成像的联合扩散光学断层扫描(DOT)与磁共振成像(MRI)系统。
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