Schwarzwald C C, Schober K E, Bonagura J D
Equine Department, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
J Vet Intern Med. 2009 May-Jun;23(3):643-52. doi: 10.1111/j.1939-1676.2009.0287.x.
Noninvasive assessment of left ventricular (LV) function is incompletely studied in horses.
The goals of this study were to investigate the feasibility, techniques, and reliability of tissue Doppler imaging (TDI) for characterization of LV radial wall motion in healthy horses.
Three Standardbreds, 3 Thoroughbreds; age 8-14 years; body weight 517-606 kg.
Repeated echocardiographic examinations were performed by 2 observers in unsedated horses using TDI. Test reliability was determined by estimating measurement variability, within-day interobserver variability, and between-day interobserver and intraobserver variability of all echocardiographic variables. Variability was expressed as coefficient of variation (CV) and the absolute value below which the difference between 2 measurements will lie with 95% probability.
Assessment of LV radial wall motion by TDI was feasible in all horses. Measurement variabilities were very low (CV < 5%) to low (CV 5-15%) for most variables. Within-day interobserver variability as well as between-day interobserver and intraobserver variabilities were low to moderate (CV 16-25%) for most variables. All pulsed-wave TDI variables of systolic LV function showed very low to low variability, whereas some of the variables of LV diastolic and LA function showed moderate to high (CV > 25%) variability. Pulsed-wave TDI variables appeared more reliable than color TDI variables.
Measurement of TDI indices of LV function is feasible and reliable in adult Standardbred and Thoroughbred horses. The clinical relevance of LV function assessment by TDI remains to be determined.
马的左心室(LV)功能的无创评估研究尚不充分。
本研究的目的是探讨组织多普勒成像(TDI)用于表征健康马匹左心室径向壁运动的可行性、技术和可靠性。
3匹标准赛马、3匹纯种马;年龄8 - 14岁;体重517 - 606千克。
两名观察者对未镇静的马匹使用TDI进行重复超声心动图检查。通过估计所有超声心动图变量的测量变异性、日内观察者间变异性以及日间观察者间和观察者内变异性来确定测试可靠性。变异性以变异系数(CV)表示,以及两次测量之间差异有95%概率会落在其之下的绝对值。
TDI评估所有马匹的左心室径向壁运动是可行的。大多数变量的测量变异性非常低(CV < 5%)至低(CV 5 - 15%)。大多数变量的日内观察者间变异性以及日间观察者间和观察者内变异性低至中度(CV 16 - 25%)。左心室收缩功能的所有脉冲波TDI变量显示出非常低至低的变异性,而左心室舒张和左心房功能的一些变量显示出中度至高(CV > 25%)的变异性。脉冲波TDI变量似乎比彩色TDI变量更可靠。
在成年标准赛马和纯种马中,测量左心室功能的TDI指标是可行且可靠的。TDI评估左心室功能的临床相关性仍有待确定。