Curthoys I S, Burgess A M, MacDougall H G, McGarvie L A, Halmagyi G M, Smulders Y E, Iwasaki S
School of Psychology, University of Sydney, Sydney, Australia.
Ann N Y Acad Sci. 2009 May;1164:344-6. doi: 10.1111/j.1749-6632.2008.03728.x.
Bone-conducted vibration of the forehead, in the midline at the hairline (Fz) causes linear acceleration stimulation of both mastoids and results in an ocular vestibular-evoked myogenic potential (oVEMP), recorded by surface electromyogram (EMG) electrodes just beneath the eyes. The early n10 component of the oVEMP is symmetrical in healthy subjects, absent in patients with bilateral vestibular loss, and in patients after unilateral vestibular loss (uVL) n10 is small or absent on the side contralateral to the uVL, but of normal amplitude on the side contralateral to the healthy ear. The n10 component probably reflects mainly otolithic function, since in the guinea pig, primary otolith irregular neurons are selectively activated by bone-conducted vibration (BCV) at low intensities (0.1 g), whereas semicircular canal primary afferents are not activated even at high intensities (10 g).
在前额发际线中线处（Fz）进行骨传导振动会引起双侧乳突的线性加速度刺激，并产生眼前庭诱发肌源性电位（oVEMP），通过置于眼睛下方的表面肌电图（EMG）电极进行记录。在健康受试者中，oVEMP的早期n10成分是对称的；在双侧前庭丧失的患者中不存在；而在单侧前庭丧失（uVL）的患者中，n10在uVL对侧较小或不存在，但在健侧对侧的振幅正常。n10成分可能主要反映耳石功能，因为在豚鼠中，低强度（0.1 g）的骨传导振动（BCV）可选择性激活初级耳石不规则神经元，而即使在高强度（10 g）下，半规管初级传入神经也不会被激活。
