Walker Mark F, Tian Jing, Shan Xiaoyan, Ying Howard, Tamargo Rafael J, Zee David S
Department of Neurology, Case Western Reserve University, Cleveland VA Medical Center, Cleveland, Ohio, USA.
Ann N Y Acad Sci. 2009 May;1164:482-5. doi: 10.1111/j.1749-6632.2008.03717.x.
In two monkeys, we recorded spontaneous eye movements before and after ablation of the cerebellar nodulus and uvula (Nod/Uv). In both monkeys, there was an increase in upward ocular drift (downbeat nystagmus [DBN]) in darkness (M1: 1.5 degrees/s pre, 3.4 degrees/s post; M2: 1.3 degrees/s pre, 7.0 degrees/s post), but not in light. There was little effect of orbital position on drift velocity. These findings suggest that the Nod/Uv may play a role in the bias component of DBN.
在两只猴子身上，我们记录了小脑小结和蚓垂（Nod/Uv）切除前后的自发性眼球运动。在两只猴子中，黑暗条件下向上的眼球漂移（下跳性眼球震颤 [DBN]）均增加（猴子1：术前1.5度/秒，术后3.4度/秒；猴子2：术前1.3度/秒，术后7.0度/秒），但在光照条件下没有增加。眼眶位置对漂移速度影响很小。这些发现表明，Nod/Uv可能在下跳性眼球震颤的偏倚成分中起作用。
