Gallicchio Lisa, Kalesan Bindu
The Prevention and Research Center, The Weinberg Center for Women's Health & Medicine, 227 St. Paul Place, 6th Floor, Baltimore, MD 21202, USA.
J Sleep Res. 2009 Jun;18(2):148-58. doi: 10.1111/j.1365-2869.2008.00732.x.
Epidemiologic studies have shown that sleep duration is associated with overall mortality. We conducted a systematic review of the associations between sleep duration and all-cause and cause-specific mortality. PubMed was systematically searched up to January, 2008 to identify studies examining the association between sleep duration and mortality (both all-cause and cause-specific) among adults. Data were abstracted serially in a standardized manner by two reviewers and analyzed using random-effects meta-analysis. Twenty-three studies assessing the associations between sleep duration and mortality were identified. All examined sleep duration measured using participant self-report. Among the 16 studies which had similar reference categories and reported sufficient data on short sleep and mortality for meta-analyses, the pooled relative risk (RR) for all-cause mortality for short sleep duration was 1.10 [95% confidence interval (CI): 1.06, 1.15]. For cardiovascular-related and cancer-related mortality, the RRs associated with short sleep were 1.06 (95% CI: 0.94, 1.18) and 0.99 (95% CI: 0.88, 1.13), respectively. Similarly, among the 17 studies reporting data on long sleep duration and mortality, the pooled RRs comparing the long sleepers with medium sleepers were 1.23 (95% CI: 1.17, 1.30) for all-cause mortality, 1.38 (95% CI: 1.13, 1.69) for cardiovascular-related mortality, and 1.21 (95% CI: 1.11, 1.32) for cancer-related mortality. Our findings indicate that both short sleepers and long sleepers are at increased risk of all-cause mortality. Further research using objective measures of sleep duration is needed to fully characterize these associations.
流行病学研究表明，睡眠时间与总体死亡率相关。我们对睡眠时间与全因死亡率及特定病因死亡率之间的关联进行了系统综述。截至2008年1月，我们对PubMed进行了系统检索，以确定有关成年人睡眠时间与死亡率（包括全因死亡率和特定病因死亡率）之间关联的研究。由两名审阅者以标准化方式依次提取数据，并使用随机效应荟萃分析进行分析。共确定了23项评估睡眠时间与死亡率之间关联的研究。所有研究均采用参与者自我报告的方式测量睡眠时间。在16项具有相似参考类别且报告了关于短睡眠与死亡率的充分数据以供荟萃分析的研究中，短睡眠时间的全因死亡率合并相对风险（RR）为1.10 [95%置信区间（CI）：1.06，1.15]。对于心血管相关死亡率和癌症相关死亡率，与短睡眠相关的RR分别为1.06（95% CI：0.94，1.18）和0.99（95% CI：0.88，1.13）。同样，在17项报告了长睡眠时间与死亡率数据的研究中，将长睡眠者与中等睡眠者进行比较的全因死亡率合并RR为1.23（95% CI：1.17，1.30），心血管相关死亡率为1.38（95% CI：1.13，1.69），癌症相关死亡率为1.21（95% CI：1.11，1.
