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骨髓增殖性疾病与高黏滞综合征

Myeloproliferative disorders and the hyperviscosity syndrome.

作者信息

Adams Bruce D, Baker Russell, Lopez J Abraham, Spencer Susan

机构信息

Department of Clinical Investigation, William Beaumont Army Medical Center, El Paso, TX 79920-5001, USA.

出版信息

Emerg Med Clin North Am. 2009 Aug;27(3):459-76. doi: 10.1016/j.emc.2009.04.001.

DOI:10.1016/j.emc.2009.04.001
PMID:19646648
Abstract

Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.

摘要

骨髓增殖性疾病和血清高黏滞综合征可迅速出现紧急症状。高黏滞血症是由循环血液中细胞成分或无细胞成分(蛋白质)的病理性升高导致的。典型的高黏滞综合征表现为出血倾向、视觉障碍和局灶性神经体征三联征。急诊医学从业者应了解这些疾病,并准备好迅速启动支持性治疗和早期的确定性管理,包括血浆置换和血液单采。早期咨询血液科医生对于管理这些复杂患者至关重要。

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