Department of Clinical Investigation, William Beaumont Army Medical Center, 5005 North Piedras Street, El Paso, TX 79920-5001, USA.
Hematol Oncol Clin North Am. 2010 Jun;24(3):585-602. doi: 10.1016/j.hoc.2010.03.004.
Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances, and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.
骨髓增生性疾病和血清高黏滞综合征可迅速表现为紧急症状。高黏滞性是由于循环血液中的细胞或无细胞（蛋白）成分病理性升高引起的。典型的高黏滞综合征表现为出血倾向、视觉障碍和局灶性神经体征三联征。急诊医学提供者应该意识到这些情况，并准备快速启动支持性和早期确定性治疗，包括血浆置换和血细胞去除。早期咨询血液科医生对于管理这些复杂的患者至关重要。
