Collipp P J, Finkelstein F, Chen S Y, Maddaiah V T
Acta Diabetol Lat. 1976 Sep-Dec;13(5-6):236-41. doi: 10.1007/BF02581120.
Potassium chloride concentrations of 100-150 mM were shown to inhibit (20-40%) human and rat liver microsomal glucose-6-phosphatase when the substrate was reduced to physiological concentration. When the enzyme was solubilized by treatment of microsomes with A12O3 the inhibition could be observed at greater substrate concentrations. Since potassium deprivation is associated with hyperglycemia in both animals and man, these observations may have physiological significance.
当底物浓度降至生理浓度时，100 - 150 mM的氯化钾浓度可抑制（20 - 40%）人和大鼠肝脏微粒体葡萄糖-6-磷酸酶的活性。当用氧化铝处理微粒体使酶溶解时，在更高的底物浓度下也能观察到这种抑制作用。由于钾缺乏与动物和人类的高血糖症有关，这些观察结果可能具有生理意义。
